The Guinea Pig is a 1929 comedy in three acts by Preston Sturges, his first play to appear on Broadway.
The Broadway production was directed by Walter Greenough and produced by Sturges.
It opened on January 7, 1929, at the President Theatre, and ran for 67 performances, closing in March of that year.
Sturges conceived of the idea for the play from personal experience, after an actress he was dating explained her erratic behavior as the result of her trying out scenarios for the play she was writing.
"[1] Sturges was unable to find a producer who wanted to mount the play, even though a production at the Wharf Theater in Provincetown, Massachusetts was a local hit, so he and his friends decided to produce it themselves, on a budget of $2,500, which was provided by a rich acquaintance.