[3] In the episode, Homer gains an operatic ability to sing following an accident, and becomes a professional and famous opera star.

Dr. Hibbert concludes that when Homer lies on his back his stomach lodges underneath his diaphragm, which in turn helps propel his powerful singing voice.

Mr. Burns overhears Homer's voice and hires him to star as Rodolfo in La bohème at the Springfield Opera House.

Homer's growing fame and success gains him loyal fans, and he gives advice to famous opera singer Plácido Domingo.

Back at home, Marge and Homer are surprised to find that the mysterious rider is a woman — Julia Eldeen (Maya Rudolph).

Although crazily obsessed with Homer, Julia proves to be a great fan club president and Marge is impressed with her efficiency.

It is shown then that he painted a version of the Sistine Chapel roof on the ceiling of his living room, with him as Adam and Marge as God.

An instrumental version of "Se il mio nome saper voi bramate" (which was being sung by Homer in the last operatic scene) plays as the credits roll over a black background.

[8] In its original American broadcast, "Homer of Seville" was watched by an average of 8.4 million viewers,[13] with an overnight Nielsen rating of 4.2 and an audience share of 11 percent.

Robert Canning of IGN gave the episode a poor review (4.5/10), finding the plot contrived and Homer's rendition of "If Ever I Would Leave You" unfunny.

[11] Richard Keller of TV Squad thought the episode was decent with several laughs, the funniest moment being when the chandelier crashes down on Julia.