The Homunculus is a fantasy novel by author David H. Keller, M.D.

It was first published in 1949 by Prime Press in an edition of 2,112 copies of which 112 were slipcased and signed by the author.

The novel concerns Colonel Horatio Bumble who has retired to his ancestral home with his wife, Helen and their Pekingese, Lady.

Colonel Bumble employs the siblings Pete and Sarah at his home.

As a result of his experiments, the Colonel is kidnapped and Sarah rescues him by employing supernatural means.