The film tells the story of brothers Clifford and Jeffrey Azize and their travels as they search for answers to the question, "What does it mean to be human?".

The first experience follows Jeffrey and his brother Clifford Azize to the streets of The Big Apple, where the boys live with the homeless for a week in one of the coldest winters on record.

Throughout the story, the film features commentary from spiritual, artistic, and medical experts and philosophers, including William B. Hurlbut M.D.

At the end of the film, the boys return to their life in New York with a changed outlook and insight into the human condition.

The Human Experience was theatrically released in select Harkins Theatres in Arizona, Colorado, and Texas on April 9, 2010 in the midst of a world screening tour.

"[2] The Archbishop of Denver released a statement on his official website endorsing the film, calling it "an astonishing witness to the beauty of the human person under the most trying conditions".

[3] Critic John Nesbit described the film as disappointing, saying the movie for relied too much on stock-footage and filler and "falls flat despite occasional memorable scenes".