His daughter Muriel is in love with an irresponsible young man named Henry Quinn, who is attempting to see her against her father's wishes.

Edward's alcoholic assistant, Dr. Anthony Finney, is secretly in love with Muriel and frames Quinn as a suspect in the recent spate of killings, leading to the young man's arrest.

"[4] Prior to directing The Hyena of London, he wrote films as early as the mid-fifties with Toto all'inferno.

[5] He debuted as a director in 1963, co-directing a political documentary on Russia with Piero Ghione,[4] shot in the Monti Parioli district of Rome, at Villa Perucchetti.

[7] In retrospective reviews, Tim Lucas referred to the film in 1989 as a "forgotten, but fascinating picture from the Italian Golden Age.