[1] It is managed by the Government of Maharashtra and is clustered from 2019 batch with the Dr. Homi Bhabha State University.

[1] Royal Institute of Science was founded by George Clarke, 1st Baron Sydenham of Combe.

The building features arched facade and includes a botanical garden, herbarium and a park.

Its research centers around all branches of science including Physics, Chemistry, Biology, Microbiology, Mathematics, Biochemistry, Bio-Technology and Environmental studies.

In Maharashtra state and University of Mumbai, some programs like the Masters in biochemistry, were available only in the Institute of Science until recently.