It was hosted by stand-up comedian Anthony Jeselnik, who extended his onstage character into weekly, topical humor with a sociopathic, dark twist.

The show primarily consisted of a monologue and two panelists who joined Jeselnik in adding a humorous take on shocking, lurid news stories.

[1] Several recurring bits are used: "Sacred Cow" is a segment that takes a subject deemed off limits, and proceeds to make several jokes about it.

[4] Jeselnik's main draw was the monologue, where he felt he could tell jokes that he was unable to do on Late Night with Jimmy Fallon, where he worked in 2009.

As such, the sketch opened the first episode and received a positive reception; Jay Leno called to inform Jeselnik how much he loved the cancer segment.

{{'"]][6] Monologue references: to Christopher Dorner's manhunt, Pope resignation, Catholic Church and HIV/AIDS, North Korea's threats of 2013, Storage Wars' Mark Balelo suicide,[7] naming of park after Ku Klux Klan's founder,[8] Detroit's Osama Bin Laden targets sale,[9] Chris Brown's Porsche crash, Navy SEAL soldier unemployed.

Monologue references: Hot Air Balloon crash - Egypt hot air balloon crash killing 19 people, Miss Teen Delaware porn video,[citation needed] Boston face transplant recipient,[14] Mindy Kaling new show, 'One Million Moms' Wants Geico Pig Commercial Pulled,[15] Carrie Fisher Bipolar episode,[16] Man who claims to have $7500 of porn stolen,[17] Joe Francis's Girls Gone Wild creator files for bankruptcy,[18] Xavier Nunez who stabbed a classmate with a screwdriver,[19] Bobby Brown convicted of DUI[20] Segments: Sacred Cow (Missing Children, with private investigator Logan Clarke[21]), Elderly Shaming, What's their problem?