In the December 5, 1950, episode, the live broadcast of a fluoroscope screen was used by doctors in New York and Chicago to diagnose the injuries to a machinist in the hospital in Baltimore.

In the April 21, 1952, episode, a scientist drank a solution containing the radioactive isotope of iodine, and then followed its progress in his own body with a Geiger counter.

The guests were sometimes national figures like Wernher von Braun (October 20, 1952), George Gamov, and Harold Urey.

According to the 1953-54 United States network television schedule, the show remained in the Wednesday at 8pm EST slot for the 1953-54 season.

[1] In 2002, Patrick Lucanio and Gary Coville wrote that, "In retrospect, Lynn Poole created one of those unique series that allowed television to fulfill its idealized mission as both an educational and an entertainment medium.

"[7] Johns Hopkins Magazine declared in 2019 that the show was "ahead of its time" for its frank approach to educating its viewers on matter of science, especially biology.