Kane is a borough in McKean County in the U.S. state of Pennsylvania, 94 miles (151 km) east by southeast of Erie.

It was founded in 1864 by Civil War General Thomas L. Kane of the famous Bucktail Regiment at an elevated site 2210 feet (674 m) above sea level.

Famous residents of Kane include Chuck Daly, two-time NBA Champion and 1992 Olympic gold medalist coach; Amy Rudolph, an Olympic distance runner and qualifier in the 1996 and 2000 Summer Games; composer Maryanne Amacher; and Evan O'Neill Kane, a surgeon known for removing his own appendix and repairing his own hernia under local anesthetic.

[5] According to the United States Census Bureau, the borough has a total area of 1.6 square miles (4.1 km2), all land.

Lake effect snow during cold snaps in early spring also helps to raise snowfall totals.

Kane is a rural community which is rich with outdoor entertainment due to its location near the Allegheny National Forest.

It is home to "Art in the Wilds", an outdoor, juried fine arts show held each year in Evergreen Park on the fourth Saturday and Sunday of June, as well as "Kane Fest", an annual festival in July formerly known as the Black Cherry Festival, which is no longer being held.

Radio stations based in and around Warren and Saint Marys are also audible in the Kane area.

In 1846, then Colonel Kane aided the Mormons on their flight west from Nauvoo, Illinois, to the Great Salt Lake; he arranged for them to winter on Indian lands near Council Bluffs, Iowa.

Thomas L. Kane was offered the Utah Territorial Governorship, but insisted that the position go to Brigham Young.

Their oldest son, Evan O'Neill Kane, M.D., demonstrated the efficacy of local anesthesia on two occasions by performing surgery on himself—once repairing an inguinal hernia, and once removing his own appendix.

[11] Due to its elevation, Kane had many summer vacationers in the 1950s and 1960s who stayed there for various periods during the late summer and fall months to avoid the effects of hay fever and allergies present at lower elevations in the days before air conditioning was prevalent.

The high school sits on the former site of General Thomas Kane's homestead, which burned to the ground in 1896.

The high school auditorium stage is roughly where Gen. Kane's front porch would have sat, looking out over the valley where the present-day football field and track sit.

The existing middle school was renovated in a multimillion-dollar project by the district, and a new elementary wing was added on the east side of the former junior high.