The Lady from Cheyenne is a 1941 American comedy western film directed by Frank Lloyd and starring Loretta Young, Robert Preston and Edward Arnold.

In the 1860s, after receiving an inheritance a Philadelphia Quaker school teacher heads west to Wyoming to establish a new school to educate settler children.

However, she encounters a corrupt tycoon who is determined to gain control of the water rights of her schoolhouse.

The film was shot at Universal Studios, and on location in the Mojave Desert.

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