Based on a story by Courtney Riley Cooper, the film is about a gangster who goes to prison and finds salvation through music while serving his time.

[2] Weary River was preserved at the Library of Congress and restored by the LoC, UCLA Film and Television Archive, and Warner Bros.

Jerry pursues a singing career in vaudeville, billing himself as the Master of Melody, but constant whispers of "Convict!"

As he prepares for a final confrontation with Spadoni, Alice gets in touch with the warden, who arrives on the scene in time to keep Jerry on the straight and narrow path.

The film features a theme song entitled "Weary River" with words by Grant Clarke and music by Louis Silvers.