It stars Laura Bailey, Taliesin Jaffe, Ashley Johnson, Matthew Mercer, Liam O'Brien, Marisha Ray, Sam Riegel, and Travis Willingham, reprising their roles from the campaign.

[8] The series received widespread acclaim from critics and audiences, with praise for its animation, voice acting, action sequences, story, writing, emotional weight, and faithfulness to the campaign.

[9][10][13] The first two episodes of the series[14] depict "an all-new story about the seven-member Vox Machina team at D&D Level 7 on their first 'grown-up' mission, which occurs prior to Critical Role's first RPG show".

As part of a sponsorship deal between Critical Role and D&D Beyond in 2018, an animated ad spot for the platform was produced which featured the Mighty Nein characters in combat.

[55] Mercer commented that "hindsight" and the expansion of Exandria's history since the original campaign allows them to incorporate later developed aspects of the lore at earlier moments in the animated adaptation.

Petrana Radulovic of Polygon highlighted the "impactful" inclusion of Zerxus Ilerez, played by Luis Carazo, who was originally created for Exandria Unlimited: Calamity – in the canon, the Calamity occurs "centuries before the events of The Legend of Vox Machina", however, Zerxus as a character "didn't even exist till five years after the original Vox Machina campaign ended, so the entire interaction with Pike is new to the show".

Radulovic noted that "the current story can now more directly seed in bigger world-building and overarching plots that will come into play down the line" since it can take the original "unscripted moments" and turn them into "more deliberate foreshadowing".

[66][67] Multiple outlets,[41][11] such as Variety,[40] the Los Angeles Times,[58] and CNBC, reported that the Kickstarter became the largest one for Film & Video, surpassing the previous record holder Mystery Science Theater 3000, with total funding of more than $11.3 million from more than 88,000 backers.

[68] The Los Angeles Times highlighted that the Kickstarter bested "bigger-name properties like 'Mystery Science Theater 3000,' revived by Netflix in 2017, and 'Veronica Mars,' which became a feature film [...].

The website's consensus reads: "Fluidly animated and intelligently scripted, The Legend of Vox Machina is an addictive treat for fans of Dungeons & Dragons-style RPGs".

Club, commented on the quality of the animation and the show's adult themes, noting that while it includes "plenty of curse words, sexual innuendo, and brutal violence—nothing feels overwhelmingly crass or unnecessarily gratuitous" and when escalation occurs, "it matters".

He commented that "while there isn't a whole lot of diversity in the principal Critical Role cast, the show comes down on the side of a kind of casual inclusivity" and that it deliberately avoids "the racial essentialism which forms more of the bedrock of tabletop roleplaying gaming than many like to admit".

Francisco commented that while Tal'Dorei as a setting might lack originality, the story has "gravitas" and highlighted Percy's arc, a gunslinger grappling with revenge, in particular as "astonishing to witness".

[72] Francisco stated that The Legend of Vox Machina is "an accessible" action fantasy "despite its sourcing from a long-running Twitch show" and is "only unusual in its marriage of Tolkien-lite settings and the lurid humor of a Deadpool comic book".

[72] Cass Marshall, for Polygon, described the show as "a deeply indulgent story", "weirdly wholesome", and at times "frankly a little much"; she also thought that the animation work carried "the plot quite well, albeit not perfectly".

[71] She expressed her love for the show, noting that "Critical Role's heart and good intentions" helped overcome The Legend of Vox Machina's "initial problems" and when the major story arc began, Marshall "was fully invested".

Marshall opined "this is D&D pulp at its best" and emphasized that viewers "don't need to delve into" Critical Role's "rich canon" to enjoy the series.

[82] Anna Govert, for Paste, stated that the 12 episode second season is a "masterclass of adaptation" as it is based on "over 80 hours of tabletop gameplay" – the series is "unafraid of making changes and knowing the importance of character-first storytelling".

[83] Govert commented that The Legend of Vox Machina's "commitment to telling [...] meaningful stories alongside its badass fight sequences and crude humor make it feel refreshing and unique still in its second outing".

[84] Radulovic highlighted that the show "might not fully gel for everyone" due to its expansive cast, huge amount of lore and raunchy comedic moments, however, "there is so much heart and fun in the grandiose adventure" which makes it special "for those it does click for".

[85] Grebey commented that Grog and Scanlan can be "a lot, especially when their antics feel degrees sillier than whatever sad emo boy thing Vax or Percy are doing.

It's all a little sillier but in a tonally consistent way, and being on their own forces the comic relief characters to step up and mature a little bit while still having the ability to pull off a pretty great suppository joke".

[87] He thought the season balanced the darker narrative aspects with humor, "heartfelt storylines", and romantic relationships and that The Legend of Vox Machina makes "viewers care deeply about the characters' fates".

[87] Rafael Motamayor of IGN saw "vengeance and love" as the main themes of the third season with death feeling "significant, poignant, utterly catastrophic, and, most importantly, costly".

[88] On the first half of the season, Motamayor thought the writers struggled "to wrangle their many ongoing storylines" while balancing "what happened on the livestreams and the changes made by the animated series" which left it "feeling too contrived and convenient at points".

[88] Harvey Randall of PC Gamer praised the unexpected character deaths as "these changes ensure that long-time fans like me aren't just sat here crossing off entries on a bingo card".

[57] Randall commented that the creators "have made a statement that no-one is exactly safe" and "while Percy's death seemed like a brave, interesting departure from the source material, turning a pretty well-loved side character into a Red Dragon pancake is like stabbing a knife through it".