Ronnie D'Addario, their father, is a musician and songwriter from Manhattan who played with Irish folk singer Tommy Makem.

The brothers were raised in a musical household and learned to play and sing at a very early age, developing an obsession with the Beatles that was passed down from their parents.

[8] In 2014, the unsigned D'Addarios approached Jonathan Rado of Foxygen on Twitter with demo recordings in hopes of attracting interest.

The Lemon Twigs served as opening act for fellow New York City/Long Island-based alt-rockers Sunflower Bean on their East Coast tour in late 2016[9] and performed on television programs like The Tonight Show Starring Jimmy Fallon, CBS This Morning "Saturday Sessions" and Conan, Jimmy Kimmel, Jools Holland, Seth Myers along the way.

In early 2017 it was announced that the band would play on day one of the Coachella Valley Music and Arts Festival in Indio, California on April 14, 2017.

[10] The Lemon Twigs released the Do Hollywood tracks "These Words" and "As Long As We're Together" as a double-A-side single, and made videos for both songs.

The band played at several major festivals in the summer of 2017, such as Glastonbury, Outside Lands, Lollapalooza, Austin City, and the Montreux,[11] in addition to opening for Phoenix across the United States.

Both Megan Zeankowski and Danny Ayala were replaced by Daryl Johns (bass), Andres Valbuena (drums) and Tommaso Taddonio (keyboards).

In March 2023, the D'Addarios backed Zombies singer Colin Blunstone at the South by Southwest festival in Austin, Texas.

The band supported the album release with a tour of North America and western Europe, concluding in London on June 1, 2023.

[24] In May 2024, the Lemon Twigs began a tour of North America and Europe in support of A Dream Is All We Know, including a string of shows opening for Lake Street Dive and a main stage performance at the Primavera Sound festival in Barcelona.

"[31] The Lemon Twigs performed on many tracks for Tim Heidecker's album Fear of Death, released on September 25, 2020, alongside Weyes Blood.

[40][41]) In 2016, The Times characterized the Lemon Twigs' early sound as "a modern-day band combining the melodic, harmony-rich soft rock of Wings and Supertramp, the underground cool of Big Star and the Ramones, and the theatricality of Broadway musicals.

"[43] A number of diverse pop music figures have publicly expressed admiration for the Twigs: Elton John,[44] the Zombies,[45] Dan and Justin Hawkins,[46][18] Boy George,[47] Gary Brooker,[48] Iggy Pop,[49] Todd Rundgren, Flea, Gerard Way,[49] Questlove, Alice Cooper,[4] Michael McDonald, and Jack Antonoff.