[2] They were one of the most influential bands on the Canadian alternative music scene in the early 1990s, garnering widespread critical acclaim and radio play.

[5] The band's punk-inspired jangle pop quickly became a popular draw on the Queen Street West club circuit in Toronto.

Hawkins's songs were filled with lyrics about Marxism and the Spanish Civil War, but also contained many references to Toronto landmarks like the Don River, Bathurst Street, and his local pub, "The Only" on Danforth Avenue.

[2] This concert was released by fans of the band as a DVD, incorporating several camcorder recordings of the show and a soundboard audio patch.

In December 2010, the band reunited again for a Massey Hall sold-out show plus two nights at Lee's Palace in Toronto to celebrate the release of a new remastered edition of Shakespeare My Butt on Pheromone Recordings.

In November 2015, they released two new songs, "The Kids Are All Wrong" and "In the Blink of an Eye", with new guitarist Brian Macmillan replacing Stanley.

[13] The Lowest of the Low have been cited as a major influence by The Weakerthans, whose leader John K. Samson was previously a member of Propagandhi when the latter covered TLotL's song "Gamble".

Covers of Lowest of the Low songs by other artists include "Rosy and Grey" by Weddings Parties Anything and "Bleed a Little While Tonight" by Jeremy Fisher.