The minimalist score makes use of songs by Robert Schumann, in particular, "Ich grolle nicht" from Dichterliebe, in which Dr. S. accompanies Dr. P., singing the ossia as a descant.

Can't mistake his body rhythm," when Dr. P. is watching television) and added documentary segments with Sacks and pathologist John Tighe working with the actual Dr. P.'s brain.

Returning from the original cast were Emile Belcourt as Dr. S. and Frederick Westcott as Dr. P. Patricia Hooper replaced Sarah Leonard as Mrs. P. The Michael Nyman Band appeared on-screen as Dr. P.'s students.

Associated with a full production of the opera, it is conducted by Dean Williamson and features singers Matthew Treviño, Rebecca Sjöwall, and Ryan MacPherson.

Members of the Nashville Opera Orchestra Dave Davidson, Connie Ellisor, Simona Rusu, Michael Samis, Sari Reist, Mary Alice Hoepfinger, and Amy Tate Williams make up the instrumental chamber ensemble.