The Man with Two Brains is a 1983 American science fiction black comedy film directed by Carl Reiner and starring Steve Martin and Kathleen Turner.

Written by Reiner, Martin, and George Gipe (who previously worked together on 1982's Dead Men Don't Wear Plaid) and shot in summer 1982 at Laird International Studios in Culver City, California, the film is a broad comedy, with Martin starring as Dr. Michael Hfuhruhurr, a pioneering neurosurgeon with a cruel and unfaithful new wife, Dolores Benedict (Turner).

On a honeymoon and business trip to a medical conference in Vienna, a city living in fear of the serial "Elevator Killer", Hfuhruhurr meets mad scientist Dr. Alfred Necessiter, who has created a technique enabling him to store living brains in liquid-filled jars using the Elevator Killer's victims.

Filling a syringe with window cleaner, the substance used by the Elevator Killer, Michael sees a crowd gathering around an attractive woman hit by a car.

Michael makes it to the lab, where Necessiter transfers Anne's consciousness to Dolores's body, which is viewed by the stunned policemen.

The site's consensus states "As spastically uneven as its zany title suggests, The Man with Two Brains isn't peak Steve Martin — but it's still often close enough to enjoy.