The Mark of Cain is a 1916 American silent lost film directed by Joe De Grasse, written by Stuart Paton, and starring Lon Chaney and Dorothy Phillips.

The film's tagline was "A Thrilling Drama of the Long Arm of the Law With an Absorbing Love Interest".

[2][3] A still exists showing Lon Chaney as "Dick Temple" skulking guiltily in the background in an office scene.

[4] Dick Temple is serving a five-year prison sentence because he took the blame for a robbery his father committed.

Suddenly Dick recognizes the old housekeeper is his mother, and he decides to thwart both groups of crooks that are planning to rob the Wilsons.