An anime television series adaptation produced by GoHands aired from July to September 2023.

The young employee Saku lives alone with her cat Yukichi, a feline as big as it is special.

Written and illustrated by Hitsuji Yamada, The Masterful Cat Is Depressed Again Today began serialization on Kodansha's Suiyōbi no Sirius online manga section on the Nico Nico Seiga website on August 22, 2018;[4] it also started publication in Monthly Shōnen Sirius on October 26, 2021.

[19] The series is produced by GoHands, who supervised the scripts written by Tamazo Yanagi, with Katsumasa Yokomine directing, Susumu Kudo serving as chief director, and Takayuki Uchida designing the characters.

[2][d] The opening theme song is "Ureu Kado niwa Fuku Kitaru" (憂う門には福来たる, "Fortune Comes to a Worried House") by Somei.