Hosted by Jojo Alejar, it aired on RJTV[1] from May 10, 2004 to October 5, 2007.

The show moved to Q from October 8, 2007 to 2008, TV5 from June 1, 2009 to September 27, 2013, GMA Network from January 6 to December 5, 2014 and later returned to TV5 from May 11 to November 6, 2015, PTV from April 30 to November 16, 2018 and RJ DigiTV since February 6, 2020.

[4] The show ended on September 27, 2013, due to the network's lineup revamp.

On January 6, 2014, The Medyo Late Night Show with Jojo A. premiered on GMA Network[5] It ran until on December 5, 2014.

[6] On November 15, 2023, the show began airing live from RJ Bistro, Dusit Thani Hotel.