Built in 1890 for John Jacob Astor III, the six-story, 84,000 square foot brick building has been cited by the New York City Landmarks Preservation Commission as an example of the Romanesque Revival period.

[2] Architect William Schickel, known for his extensive work on behalf of the Archdiocese of New York, designed the building as offices for the vast Astor family holdings, resulting in a façade considerably more ornate than its industrial neighbors.

[6] The overall aesthetic allows The Mercer to be "the first hotel to offer an authentic taste of loft living", an urban signature that is completely original to New York.

[8] Chef Jean-Georges Vongerichten was recruited by André Balazs as the head of restaurant and food service for the property.

[8] The Mercer Kitchen provides room service throughout the hotel while the upper level café serves breakfast and lunch daily.