It consisted of an alphabetically arranged collection of humor pieces, cartoons, and comic strips that had been especially created by many of the National Lampoon's regular contributors.

It included written pieces by Michael O'Donoghue, P. J. O'Rourke, Terry Southern, Anne Beatts, Doug Kenney, and Brian McConnachie.

There were cartoons by B. Kliban, M. K. Brown, Ed Subitzky, Brian McConnachie, John Caldwell, Bobby London, and Sam Gross.

In addition there was artwork by Edward Gorey, Bruce McCall, Rick Meyerowitz, and Vaughn Bode.

The book also included a pull-out: the National Lampoon Map of the World.