Together with a team of Galactic Guardians from Primus, He-Man fights to defend the planet and all its power resources from the continuous attacks by Skeletor and the Mutants.

The element of the transformation from Adam to He-Man is retained from the first cartoon series, as the makers felt it would be unwise to abandon it given that the transformation sequence had been one of the most popular elements of the original series.

[9] BCI Eclipse LLC (under its Ink & Paint classic animation entertainment brand) (under license from Entertainment Rights) released The New Adventures of He-Man on DVD in Region 1 in two volume sets in 2006/2007.

Each episode on BCI Ink & Paint's DVD releases of The New Adventures of He-Man (AKA He-Man in Space by He-Man fans) was uncut and digitally re-mastered for optimum audio and video quality and presented in its original broadcast presentation and story continuity order, as well as extensive bonus features.

[10] To commemorate the 30th anniversary He-Man and the Masters of the Universe brand, Mill Creek Entertainment released the 30th Anniversary Commemorative Collection of He-Man and the Masters of the Universe DVD in December 2012.