[1] It had a house band called Bight, Chew & Spit,[2] and hosted artists including The Commodores and The Bar-Kays, and played recorded disco and funk featured by DJs from one of the few Black-owned radio stations in the country, WBMU-FM.

In 2015, The Orange Peel expanded its booking efforts and began partnering with local breweries to host large outdoor concerts.

The two venues have since parted ways as Asheville Pizza has canned all Orange Peel staff and any ties with the opening of "The Backdoor".

Black Emperor,[11] 311 (in 2008, 2009 x2 & 2011), Modest Mouse, Tegan and Sara, Black Label Society, Umphrey's McGee in 2003, Bob Dylan in 2004, Chevelle in 2005, Smashing Pumpkins (residency in 2007), the Beastie Boys in 2009, The Black Keys, Lauryn Hill in 2017, Ice Cube, Skrillex, Deadmau5, Bassnectar, Pretty Lights, The Glitch Mob, Wax Tailor, Medeski, Martin, and Wood, Queens of the Stone Age in 2007, Mastodon in 2011, Breaking Benjamin in 2017, Megadeth, GWAR, Lamb of God, Decapitated, Silversun Pickups in 2016, The Dirty Heads, The Struts, AJR in 2018, Buckethead in 2018 and King's X in 2023.

The Orange Peel has also hosted Asheville's Warren Haynes in 2013 for the Christmas Pre-Jam, Asheville's Luke Combs in 2016, Asheville's Chase Rice in 2017, Rainbow Kitten Surprise in 2018, Ben Folds in 2009, Daughtry in 2008, Southern Culture on the Skids in 2002, Ben Taylor (son of James Taylor) Band in 2003, Avett Brothers in 2008, Carolina Chocolate Drops in 2012, Kellie Pickler in 2011, Greenville's Edwin McCain in 2003, Knoxville's 10 Years in 2008, Nashville's Kings of Leon in 2007, Moon Taxi in 2016, Judah & the Lion in 2018, Columbia's Hootie & the Blowfish in 2003, Toro y Moi in 2018, Charleston's Jump, Little Children in 2003, Band of Horses in 2009, Duncan Sheik in 2003, Trevor Hall in 2006, Atlanta's Manchester Orchestra in 2014, Gregg Allman Band in 2002, Chris Robinson Brotherhood (Black Crowes singer) in 2015, Indigo Girls in 2017, and Virginia's Jason Mraz in 2005.