[3] The Passage focuses on Project Noah, a secret medical facility where scientists are experimenting with a dangerous virus that could lead to the cure for all disease, but also carries the potential to wipe out the human race.

When a young girl, Amy Bellafonte, is chosen to be a test subject, Federal Agent Brad Wolgast is tasked with bringing her to Project Noah.

It likewise brings them face-to-face with a dangerous new race of beings confined within the walls of Project Noah, including former scientist Tim Fanning and death-row inmate Shauna Babcock.

As Project Noah's scientists home in on a cure that could save humanity, these new beings begin to test their own powers, inching one step closer to an escape that could lead to an unimaginable apocalypse.

[18] In June 2017, Mark-Paul Gosselaar, Saniyya Sidney, Genesis Rodriguez, Brianne Howey, B. J. Britt and Jennifer Ferrin were announced to have been cast in the pilot.

The website's critical consensus reads, "Strong performances from leads Mark-Paul Gosselaar and Saniyya Sidney can't course correct The Passage's wayward plot and feeble tone.