The film was directed by Brenda Chapman, Steve Hickner, and Simon Wells, and written by Philip LaZebnik, from a story by Kelly Asbury and Lorna Cook.

To make the project, DreamWorks employed artists who had worked for Walt Disney Feature Animation and Amblimation, totaling a crew of 350 people from 34 countries.

The film's success led to the direct-to-video prequel Joseph: King of Dreams (2000), and a stage musical adaptation which opened in London's West End in 2020.

The film also won the inaugural Critics' Choice Movie Award for Best Animated Feature, in a tie with Disney and Pixar's A Bug's Life.

Yocheved and her children, Miriam and Aaron, rush to the Nile River, where she places her newborn son in a basket on the water, bidding him farewell with a final lullaby.

God inflicts eight more plagues onto Egypt: frogs, lice, flies, livestock pestilence, boils, hailfire, locusts, and prolonged darkness, but still Rameses refuses to relent, vowing never to release the Hebrews.

Beginning with a starting outline, story supervisors Kelly Asbury and Lorna Cook led a team of fourteen storyboard artists and writers as they sketched out the entire film—sequence by sequence.

Once the storyboards were approved, they were put into the Avid Media Composer digital editing system by editor Nick Fletcher to create a "story reel" or animatic.

[27] Because DreamWorks was concerned about theological accuracy, Katzenberg decided to call in Biblical scholars, Christian, Jewish, and Muslim theologians, and Arab American leaders to help his film be more accurate and faithful to the original story.

[27] The backgrounds department, headed by supervisors Paul Lasaine and Ron Lukas, oversaw a team of artists who were responsible for painting the sets/backdrops from the layouts.

[27] While Katzenberg took the rest of the crew members to Egypt, the background supervisors visited Death Valley, California to study the colors, textures and landscapes.

In March 1995, as a temporary solution to accommodate increases in crew members, the studio was moved into the Lakeside Plaza facility, nearby on the lot.

Various tracks by contemporary artists such as K-Ci & JoJo and Boyz II Men were added, including the Mariah Carey and Whitney Houston duet "When You Believe", a Babyface rewrite of the original Schwartz composition, sung by Michelle Pfeiffer and Sally Dworsky in the film.

[43] The international release occurred simultaneously with that of the United States, as according to DreamWorks' distribution chief Jim Tharp, opening one week prior to the "global holiday" of Christmas, audiences all over the world would be available at the same time.

[45] Walmart served as a promotional partner and offered in stores a package featuring two tickets to The Prince of Egypt, a storybook and the film's soundtrack.

[47] The Prince of Egypt: Classic Edition storybook, published by Dutton Children's Books in 1998, was written by Jane Yolen and illustrated by Michael Koelsch.

[58] The opening was seen as somewhat disappointing given the film's high production and promotional costs, as well as the studio's faith in the project, and industry insiders had doubts it could leg out to $100 million domestically.

The website's critics consensus reads: "The Prince of Egypt's stunning visuals and first-rate voice cast more than compensate for the fact that it's better crafted than it is emotionally involving".

It employs computer-generated animation as an aid to traditional techniques, rather than as a substitute for them, and we sense the touch of human artists in the vision behind the Egyptian monuments, the lonely desert vistas, the thrill of the chariot race, the personalities of the characters.

[66] Stephen Hunter from The Washington Post praised the film saying that "the movie's proudest accomplishment is that it revises our version of Moses toward something more immediate and believable, more humanly knowable".

[67] Lisa Alspector from the Chicago Reader praised the film and wrote: "The blend of animation techniques somehow demonstrates mastery modestly, while the special effects are nothing short of magnificent".

[68] Houston Chronicle's Jeff Millar praised the animation of Prince of Egypt and called it "an amalgam of Hollywood biblical epic, Broadway supermusical and nice Sunday school lesson".

[70] Liam Lacey of The Globe and Mail gave a somewhat negative review, writing that Prince of Egypt is spectacular but that the film takes itself too seriously.

[12] Lisa Laman of Collider wrote that it "stands out" among the other films in DreamWorks Animation's catalog for its dark but inspirational and uplifting tone when compared to the studio's later titles.

[76] Hannah Shortt of MovieWeb ranked it at number 8 on her list of the "Best Animated Movies From the 1990s", commenting that placing Moses and Ramases' relationship as brothers at the forefront of the film's focus helped make the story feel new and fresh for a modern audience.

[77] Jacob Oller of Paste named it the third-best DreamWorks Animation film of all time, calling it "dark, beautiful, and filled with songs as epic as its visuals".

[79] The Prince of Egypt saw a resurgence in visibility during the COVID-19 pandemic in 2020, most notably when Cynthia Erivo and Shoshana Bean, with piano accompaniment by Stephen Schwartz, performed a rendition of "When You Believe" during the virtual Saturday Night Seder that April, in response to the shutdown of Broadway and the film's stage musical adaptation suspending performances in the West End.

[83] In November 2021, the "River Lullaby" leitmotif became the subject of a TikTok mash-up between that and Hans Zimmer's "Gom Jabbar" score cue from the film adaptation of Dune, created by Nashville singer JADA.

The project began during production of The Prince of Egypt, employing some of the same animation crew and featuring director Steve Hickner as an executive producer.

[108] The production was filmed by Universal Pictures Content Group and STEAM Motion + Sound for a future broadcast, and was released in theaters on October 19, 2023.