[3] As of 2017, the band's lineup features the three original members: Gregory Grene (button accordion and lead vocals), Andrew Harkin (bass), Brian Tracey (drums), plus Galway's Dave Fahy (guitar and lead vocals) who has been a member since 2009.

They are frequently joined by Alex Grene, nephew of Gregory, and a graduate in music composition from the University of Chicago.

The Prodigals call Paddy Reilly's (the world's only all-draft Guinness bar) their home when in New York City.

The band has its own distinctive sound, particularly distinguished by lead melodic roles being filled by button-key accordion and bass along with the vocals, and has received substantial critical notice through the years.

Their songs "Open Reel" and "The Bunch of Red Roses" were played in the film Pride and Glory during the bar fight scene between Edward Norton and Colin Farrell.