She brings various celebrities on screen to discuss their accomplishments in the entertainment, sports, and media industries.

Ray asks for tips and strategies for staying healthy and safe from various health and lifestyle experts, she includes make-over segments, and features musical performances, all of which are features along the same lines of The Oprah Winfrey Show.

On March 9, 2007, Entertainment Tonight revealed that the show's theme music was written and recorded by Ray's husband, John Cusimano.

The original theme song to the show was performed by R&B, Soul and Jazz group The Neville Brothers.

[5] Rachael Ray was the only one of the four syndicated daytime talk shows that premiered for the 2006–07 season to be renewed.