Controlling the boy, the player must feed the blob different flavored jelly beans to transform it into different tools to traverse the castle.

The Rescue of Princess Blobette was designed and programmed by David Crane, who also created the original NES game.

[4] The boy can only run back and forth, cannot jump or swim, and will die if he falls a long distance or comes in contact with dangerous objects such as flamethrowers and sewer serpents.

For example, feeding the blob a tangerine jelly bean will change him into a trampoline, which the boy can then use to reach high platforms.

[13] Ed Griffiths of Nintendojo felt the game's graphics and sound to be very plain, but found gameplay mix of puzzles and exploration satisfying for first time players.

[5] 1UP.com writer Ray Barnholt, who is familiar with the original A Boy and His Blob, was thoroughly unimpressed with The Rescue of Princess Blobette.

Barnholt disliked the limited room to move, the ability of the blob to accidentally push the boy into a deadly trap, and no way to save one's progress.