It stars Nathan Purdee as Youngblood Priest (replacing Ron O'Neal from the two previous films) and Margaret Avery.

Joey Maxwell, Manuel, and Reynaldo invade a New York City drug den in Harlem, killing three dealers.

Reformed drug dealer Youngblood Priest, who has been living in Paris, France, for the past decade, returns to New York City for Eddie's funeral.

He telephones Tom Perkins, his former lawyer, who arranges a meeting with New York City Police Department Inspector Wolinski.

Youngblood Priest goes to the penthouse apartment of his old friend, Armando, and finds a beautiful woman, Irene, taking a shower.

Nate laments that most of their friends are dead or in prison, but Joey Maxwell, one of Priest's former employees, has become the henchman for drug kingpin Hector Estrada.

Returning to Tom Perkins's office, Priest meets another of the lawyer's clients, a club owner named Francine.

Noticing that two white policemen, Mike and Ike, are following him, Priest drives into the garage of an apartment building, parks, and tries to elude them on foot, but the officers stop him in an alley and beat him.

Louis, the white plainclothes policeman who saved him from Mike and Ike, alerts Priest that the killers went to the penthouse to kill him, not Irene.

Dressed in camouflage clothes, Willy greets Priest with a shotgun, but recognizes his name from stories Eddie told him.

When Maxwell struggles, Priest knocks him unconscious, empties his wallet, gives all the money to Jasmine, and tells her to take a vacation.

Willy straps a nitroglycerin bomb around Joey Maxwell's neck, and Priest warns him that the wrong move could blow his head off.

While Willy distracts the security guard, Priest climbs a fire escape, breaks into Maxwell's office, and mixes something into a large, plastic container of crack cocaine.

The next morning, Tom Perkins advises Hector Estrada to "lay low" until the violence subsides, because the DEA is investigating.

Manuel and Reynaldo break into Willy's house, shoot him, and free Joey Maxwell, who revives his spirits by inhaling drugs, not realizing they are contaminated.

Tom Perkins and Hector Estrada are offered deals in return for their cooperation to inform on the entire "Colombian set-up."

[4][5] A soundtrack containing hip hop music and songs by Curtis Mayfield was released on August 13, 1990 by Capitol Records.