It stars Léa Seydoux, Vincent Lindon, Louis Garrel, Raphaël Quenard and Manuel Guillot.

In January 2024, Léa Seydoux revealed in an interview with Télérama that she had recently completed two weeks of filming for an unannounced new film by Quentin Dupieux, then titled À notre beau métier ('To Our Beautiful Profession'), which would also star Vincent Lindon, Louis Garrel and Raphaël Quenard.

Seydoux read the script in one sitting and quickly accepted the role out of admiration for Dupieux whom she described as an "extraordinary filmmaker" whose style of humour "hides an increasingly social depth, through imperfect and clumsy characters."

[6] Thierry Bordes of Ciné Passion en Périgord, an association which supports film productions in Dordogne, claims that Dupieux has made "the longest tracking shot in the history of cinema" in The Second Act.

[7] Hugo Sélignac produced the film through his company Chi-Fou-Mi Productions,[3] It was co-produced by Arte France Cinéma.