[1][2][3] It airs 2 to 4 times per week, is hosted by Dr. David Livingston (born June 4, 1946),[4] and features live guest interviews with call-in and email questions from listeners.

According to Livingston, the show started in 2001 as Business without Boundaries on a small Arizona radio station, which added Internet audio streaming later.

Frequent guests on the show include: science journalist and historian Robert Zimmerman,[5][6] physicist Dr. John Brandenberg,[7][8] and engineering professor Dr. Haym Benaroya.

[16] Philip Harris has described the show as "a platform for knowledgeable, educational exchanges on humanity's space future and opportunities".

[3] In 2004, Fraser Cain, publisher of Universe Today and co-host of Astronomy Cast, described The Space Show as a "favorite" and that he was "astonished and jealous at the caliber of guests".