Oscar Isaac stars as Marc Spector and Steven Grant, alongside May Calamawy as Layla El-Faouly and Ethan Hawke as Arthur Harrow.

Steven Grant and Layla El-Faouly find a deserted camp site at the location of Ammit's tomb, which is a maze in the shape of the Eye of Horus.

Layla defeats the priests but encounters Harrow, who claims that her husband Marc Spector was one of the mercenaries who murdered her archaeologist father, Abdallah El-Faouly.

[5] Executive producers include Marvel Studios' Kevin Feige, Louis D'Esposito, Victoria Alonso, Brad Winderbaum, and Grant Curtis, star Oscar Isaac, Diab, and head writer Jeremy Slater.

Speaking to when Marc Spector finds Steven Grant and they embrace, Moorhead noted much of the series had been the antagonism between them, and this was meant to show the two were "starting to learn to work together and gain some mutual respect".

Benson and Moorhead requested more material for the in-universe Tomb Buster film than was originally written, so they could have it play in the background if needed.

[9] The episode stars Oscar Isaac as Marc Spector and Steven Grant, May Calamawy as Layla El-Faouly, Khalid Abdalla as Selim, Ann Akinjirin as Bobbi Kennedy, David Ganly as Billy Fitzgerald, Antonia Salib as Taweret, and Ethan Hawke as Arthur Harrow.

[10][11]: 47:56–48:17  Also appearing are Lucy Thackeray as Donna, Shaun Scott as Crawley, Loic Mabanza as Bek, Joseph Millson as Dr. Grant, and Bill Bekele as Rosser.

[15] Filming took place at Origo Studios in Budapest,[6]: 8  with Benson and Moorhead directing,[4] and Andrew Droz Palermo serving as cinematographer.

The directors wanted to ensure there was a creepy factor to the mental facility scene and that it felt like it was underwater, using slow camera movements and shots meant to replicate Spector's point of view.

However, after filming Isaac's coverage, they saw "what he was giving us and ... how active it was", including having a real fly land on his hand, and refocused how they planned to edit the sequence to make it more about Spector's experience.

[24] Whip Media, which tracks viewership data for the more than 25 million worldwide users of its TV Time app, calculated that Moon Knight was the top streaming original series for the week ending April 24.

"[26] Maggie Boccella of Collider gave the episode an "A+", saying "the show is officially ramping up in a way that Marvel never has before, opening the door for something new and dangerous that once again threatens the universe as we know it".

In conclusion Fowler said "Moon Knight pulls from the pages of one of our hero's craziest comic arcs to drop a much-needed bomb on the adventure".

However, he felt that the scenes were made better with the Moon Knight suit unavailable because it resulted in "tense conversations and one attack from a very scary being" that forced the character's to be their resourceful selves.