The episode guest stars Brett Goldstein, Lois Chimimba, Suzanne Packer, Ben Bailey-Smith, David Shields, and Jack Shalloo.
Helped by Mabli, Astos' colleague, the Doctor learns that the entity is a Pting, a creature that eats non-organic material and is classed as highly dangerous.
While Yasmin and Ronan defend the ship's power source from the Pting, Ryan and Graham offer to help Mabli with Yoss as he enters labour.
"[1] After the premiere episode, "The Woman Who Fell to Earth", was broadcast, it was announced that Brett Goldstein, Lois Chimimba, and Ben Bailey-Smith would be among a number of guest actors that would appear in the series.
"The Tsuranga Conundrum" also guest stars Suzanne Packer as Eve Cicero, David Shields as Ronan, and Jack Shalloo as Yoss Inkl.
[3] To help with filming the episode, production staff invited Australian director Jennifer Perrott to come over and oversee the directing of scenes for "The Tsuranga Conundrum".