The governance was modelled on the provincial University of Toronto Act of 1906 which established a bicameral system of university government consisting of a senate (faculty), responsible for academic policy, and a board of governors (citizens) exercising exclusive control over financial policy and having formal authority in all other matters.

George Creeford Browne (architect) & S. Frank Peters designed Wesley Hall (1894–5), which is now part of the University of Winnipeg.

The Buhler Centre was constructed to house the Faculty of Business and Economics, as well as PACE (Professional, Applied and Continuing Education), a division of the University of Winnipeg.

[10] Designed by PSA+DPA+DIN collective a collaborative effort between Peter Sampson Architecture Studio inc, David Penner Architect, and DIN Projects.

The Buhler Centre also houses the Plug In Institute of Contemporary Art and Stella's Cafe on the main floor.

"[15] The UWCRC is a not-for-profit subsidiary of the University of Winnipeg and works to achieve environmental, social, economic and cultural sustainability.

Their mandate is to "apply [the UWCRC's] values, skills, competencies, and experience to non-University specific economic development activities.

[16] The corporation serves as "a primary engine for the redevelopment of Winnipeg's downtown", a task traditionally undertaken by government and the private sector, and not educational institutions.

[16] Recent initiatives include the newly renovated Asper Centre for Theater and Film, Richardson College for the Environment and Science Complex, The Axworthy Health and RecPlex, McFeetors Hall (a new student residence) and the UWSA Daycare.

[15][17] The University of Winnipeg is a provincially and privately funded post-secondary institution with undergraduate and a growing number of graduate programs including Canada's only master's degree in development practice with a focus on Indigenous development, as well as a professional, applied and continuing education and a high school division.

It has Canada Research Chairs in Fundamental Symmetries in Subatomic Physics, Quantum Materials Discovery, Culture and Public Memory, Human-Environment Interactions, Health & Culture, Indigenous People, History and Archives, Environmental Influences on Water Quality, and in Indigenous Arts, Collaboration and Digital Media.

[33] Through its Wii Chiiwaaknak Learning Centre, Eco-Kids Program and Eco-U Summer Camp services, the University of Winnipeg actively partners with Aboriginal communities.

[37] The university is represented in U Sports by the Winnipeg Wesmen in volleyball, basketball, soccer, wrestling, as well as baseball.

The U of W built a new field house (" The RecPlex"), named after Lloyd Axworthy, adjacent to the Duckworth Centre that provides indoor soccer services and smoothies.

The rock climb is traditionally held at the beginning of classes each year, on the front lawn of Portage Commons.

[40] The library facility occupies the 4th and 5th floors of Centennial Hall, which was featured on the March 1973 cover of Progressive Architecture.

The mission of the gallery is to, "engage diverse communities through the development and presentation of contemporary and historical art exhibitions and related programming initiatives.