"The Vampyre of Time and Memory" is a song by the American band Queens of the Stone Age, from their sixth studio album, ...Like Clockwork.

"[4] Leonie Cooper of NME wrote that the song "is a startlingly low-key piano hymnal, even with its flashes of Giorgio Moroder synths and cocaine-soul guitar solo," while comparing the confessional lyrics and the power ballad melody to the works of Fleetwood Mac.

"[8] In his track-by-track review, Gary Graff of Billboard wrote: "This dark power ballad starts with just Homme's voice and piano before filling out into an angsty but tuneful lament.

"[9] Sharon O'Connell of Uncut stated that elements of electronica are added to a backdrop of the song "that taps, Eric Clapton, Queen and early-’70s Elton John.

[12] The video shows "embalmed-looking Josh Homme" and rest of the band performing in a set of increasingly macabre locales, including "a taxidermist’s parlor," accompanied by "two maids and one voodoo priestess.