The film stars Olivia Taylor Dudley, Michael Peña, Dougray Scott, Djimon Hounsou, Peter Andersson, Kathleen Robertson, and John Patrick Amedori, and was released on July 24, 2015, by Lionsgate.

In the Vatican, Vicar Imani shows Cardinal Mattias Bruun the case of Angela Holmes, a young American woman who is suspected of harboring an evil spirit.

Angela's possession becomes worse; she taunts her psychiatrist, Dr. Richards, eventually culminating in her speaking in Aramaic that induces hysteria and mass suicide in her fellow patients.

Cardinal Bruun concludes that Angela is possessed by the Antichrist due to the presence of the ravens around her, which are agents of Satan, and instructs Imani to stay back while he heads to the United States to cure her.

An exorcism he plans involves a Eucharist, where Angela reacts by vomiting blood and spitting three eggs, meant to symbolize a perverted Trinity.

[6][7] The Vatican Tapes opened theatrically on July 24, 2015 in 427 venues, earning $832,271 in its first weekend, ranking fifteenth in the United States box office and last among the week's new releases.