[3][4][5] Originally designed by architect Philip Johnson and noted acoustician Cyril M. Harris, the $32 million building opened in 2008 as the home of the now defunct Pennsylvania Academy of Music.

[6][4][7] The building became available due to the bankruptcy of the PA Academy of Music at the same time Millersville University was planning an extensive renovation of its main campus arts center.

[8][9][10] The Pennsylvania Department of General Services then bought the building from Union Community Bank on Millersville's behalf for $10.9 million in March 2011.

[8][10] The building plays host to various musical, theatrical, dance, poetry, lecture, and other artistic events throughout the year, including on Lancaster city’s First Fridays.

[19] Due to its close proximity to Gallery Row in downtown Lancaster, The Ware Center has taken a lead in promoting arts within the city.