The first series was published by Topps Comics and ran for 41 issues from January 1995 to September 1998, coinciding with the second through fifth seasons of the television program.

I rarely ran negative letters in these columns because the [Topps] editors were afraid that the X-Files people would want even more changes in the material.

"[2]The digest consisted of three issues published at five month intervals beginning December 1995 through September 1996, each featuring separate titles: "Big Foot, Warm Heart", "Dead to the World", and "Scape Goats".

It was a one-shot timed with the release of the second film, written by Frank Spotnitz with art by Brian Denham.

[4] This became a six-part series that ran from November 2008 to April 2009 with Spotnitz writing the first two issues, Marv Wolfman for #3–4, and Doug Moench for #5–6.

IDW then went on in July 2013 to begin publishing The X-Files Season 10[6] as an ongoing series reuniting Mulder and Scully with creator Chris Carter returning as executive producer.

A review of the first Checker Book volume is complimentary about the writing and art, but scathing about the production values of the book itself, stating that "this collection from Checker reflects a lack of editorial control, poor workmanship, and generally shoddy values".