The series stars Ian Somerhalder, Adrian Holmes, Jacky Lai, Kyle Breitkopf, Peter Outerbridge, Kimberly-Sue Murray and Sydney Meyer.

[3] The outbreak is caused by an ancient biological infectious agent, a prion, that turns humans into vampires,[4] released from ice by climate change.

Additional executive producers were set to include Brad Turner, Eric Birnberg, Thomas Walden, David Ozer, Ted Adams and James Gibb.

Notable authors who contributed short stories to the series include Maberry, Jennifer Brozek, Larry Correia, Keith R. A. DeCandido, John Everson, Gregory Frost, Nancy Holder, Jeff Mariotte, Joe McKinney, James A. Moore, Yvonne Navarro, Scott Nicholson, Weston Ochse, Jeremy Robinson, Scott Sigler, John Skipp, and Tim Waggoner.

[18] Isaac Feldberg at The Boston Globe enjoyed it, calling it "unabashedly silly...a fun, freaky B-movie stretched out to series’ length".

[25] WhatCulture described the series "a thrilling well-paced ride...[and] damn good fun that compels you to keep watching" despite "moments that temporarily draw focus from the plot and leave you scratching your head".