A parish of the church included 250 houses in Kryvyi Rih and also 2 villages in the neighbouring Yekaterinoslav Governorate – Shmakovo (Pokrovskoe) and Dubovaia Balka.

With the beginning of the Russian Revolution, parson priest Mikhail Pukhalsky was killed together with his wife Maria after three hours of torture in his parsonage at the churchyard in March 1918.

In 1929, the town executive committee received peasant's requests for turning the church into a rural club, and in 1930, the possibility of founding an antireligious university on its base was also considered.

Services were held in a private house on 18 Kirov Street until 1938 when all clergy was repressed by agencies of the NKVD (the Peoples’ Commissariat for Internal Affairs in the Union of Soviet Socialistic Republics).

In this period, the parish had 4,000 members and was headed by archpriest Stefan Yanovsky, who was also the Dean of the Kryvyi Rih district of the Dnipropetrovs’k diocese.

In the spiritual enlightenment centre, there are youth and two children's choirs along with art studio which have become laureates of All-Ukrainian and international festivals and competitions (in Ukraine, Russia, Poland and Serbia).

Publications range from studies about churches in Kryvyi Rih, educational programmes and methodological recommendations for Sunday schools, and a musical collection with hymns and songs for a choir outside of the Liturgy.

Kryvyi Rih painters such as Ivan Avramenko, Dmytrii Grybok, Alexander Udovenko and Oksana Kolos found creative inspiration for their painting there.