[1] Singleton has been involved in the excavation of slave residences in the southern United States and in the Caribbean.
[2][3] She is a professor of anthropology at Syracuse University, and serves as a curator for the National Museum of Natural History.
[5] In 1991, Singleton worked as an associate curator of historical archaeology for the Smithsonian Institution.
[7] Singleton and Elizabeth Scott created the Gender and Minority Affairs Committee in the Society for Historical Archaeology.
[3] The Journal of American History called The Archaeology of Slavery and Plantation Life (1985), edited by Singleton, "a notably coherent group of papers that allow historians to look in new and stimulating directions to analyze the past.