Breslin won the annual Carnegie Medal from the Library Association, recognising it as that year's best children's book.

[5] Breslin was appointed Officer of the Order of the British Empire (OBE) in the 2019 Birthday Honours for services to literature.

[citation needed] Divided City (2005) is her eighth book for the Doubleday list.

The Medici Seal, (August 2006) for which her research was extensive, with trips to study Leonardo da Vinci’s most famous works, including the Mona Lisa and The Last Supper.

The Medici Seal is a tale of intrigue, murder and betrayal which follows the journey of Matteo as he travels with Leonardo across Italy on the Borgias' business.