Another merger occurred between Pfizer's and GlaxoSmithKline's consumer healthcare divisions, and the brand was sold to the Italian pharmaceutical company Angelini in 2021.
[2][3] In a low back pain study conducted at the U.S. Spine & Sport Foundation in San Diego, California in 2006, participants treated with Continuous Low-level Heat-wrap Therapy (CLHT) prior to exercise reported less intense pain and less trouble moving after 24 hours than the control group.
[citation needed] When applied to the lower back muscles, it provided greater pain relief for 24 hours after application when compared to ibuprofen, acetaminophen, and no treatment.
[citation needed] It was developed in 1997 as a portable heat wrap for the treatment of back pain that didn't use counter-irritants such as menthol or capsaicin.
It's designed as a cloth wrap that houses several small disks made of iron powder, activated charcoal, sodium chloride, and water.