Before disbanding in 2009, they released three studio albums: Oxeneers or the Lion Sleeps When Its Antelope Go Home (2004), Easter (2006) and Tail Swallower and Dove (2008).

Former members of These Arms Are Snakes currently play in Russian Circles, Narrows, Minus the Bear, Crypts, Dust Moth, and Hooves.

They toured with the bands Minus the Bear, Big Business, Mastodon, Cursive, The Blood Brothers, Engine Down, Hot Water Music, Isis, Pelican, Chiodos, and Against Me!.

The band formed as a five-piece in 2002 with Steve Snere of Kill Sadie, Brian Cook of Botch, and Ryan Frederiksen of Nineironspitfire in addition to Joe Preston and Jesse Robertson.

Before recording their follow-up album to This Is Meant to Hurt You, Joe Preston also left the group and was replaced by Erin Tate who played in Kill Sadie with Steve Snere and Minus the Bear.

In support of Oxeneers, These Arms Are Snakes joined the "Totally Badical Tour" with headliner Underoath and openers The Chariot, Hopesfall, and Fear Before the March of Flames.

The members of Underoath were at the time ardent Christians, openly expressing their thoughts on religion and politics and frequently conflicting with the ideals of These Arms Are Snakes.

[9] Over their former label, they praised Suicide Squeeze's treatment of the band and ability to market and sell records, in addition to being with more familiar groups like Minus the Bear.

Prior to disbanding, These Arms Are Snakes had expressed interest in taking their music in a new direction for a potential fourth studio album,[22] with writing and recording expected to begin in December 2009.

[9] Also in 2009, the group announced they had recorded tracks for a split with Minus the Bear and a compilation covers album paying tribute to Nirvana's In Utero[22]—both of which were unreleased at the time of the band's break up.

After seven years of "extended delays and legal wrangling," Robotic Empire released In Utero, in Tribute, in Entirety on Record Store Day 2014, which features These Arms Are Snakes' cover of Nirvana's "Heart-Shaped Box.