[3] The femur is categorised as a long bone and comprises a diaphysis, the shaft (or body) and two epiphyses, the lower extremity and the upper extremity of femur, that articulate with adjacent bones in the hip and knee.

These compartments use the femur as an axis and are separated by tough connective tissue membranes (or septa).

[8] Thigh injury resulting from sports, whether acute or from overuse, can mean significant incapacity to perform.

Runner's knee (patellofemoral pain) is a direct consequence of the kneecap rubbing against the end of the thigh bone (femur).

Strategic covering or display of thighs is used in popular fashion around the world, such as thigh-high boots and zettai ryoiki.