On 14 October 2016, Dafydd Elis-Thomas left Plaid Cymru in order to support the coalition government and to give them a ruling majority; he later sat as an independent in the Senedd.

The government was replaced by the Drakeford government on 13 December 2018, following the resignation of Carwyn Jones as First Minister the previous day.

[1] Following negotiations with the Plaid Cymru leader, a second vote on 18 May saw Jones re-elected unopposed as First Minister, enabling him to begin the process of forming a minority government.

[4] He was sworn in as First Minister on 19 May, after which he said that he was "delighted to introduce the team who will be taking Wales forward over the next five years".

Among his appointments was the former Welsh Liberal Democrat leader Kirsty Williams, who became Minister for Education.