[2] The film is produced by GP Ravi Kumar, Chinta Gopala Krishna Reddy and Raja Senthil under GPRK Cinemas banner.

Manickam is a righteous man who runs a lottery shop at the Kumily bus stand, supporting his family consisting of his wife, Sumathi, and two daughters.

An impoverished elderly man, whose pregnant daughter, Valli was abandoned by her husband over dowry issues, visits Manickam's shop.

Despite Sumathi's resistance citing the unpaid debt and her brother Chandru's attempted intervention, Manickam resolutely boards a bus to Idukki to hand over the ticket to the elderly man.

En route, he meets Gurumoorthy, an NRI who questions the practicality of Manickam's quest, given the uncertainty of finding the elderly man.

Manickam escapes before SI Rajendran arrives and successfully hands over the lottery ticket, saving the elderly man's daughter from committing suicide.

The ruling party of Kerala covers Vaanathi's medical expenses, and a builder friend of the Chief Minister offers Manickam's family a residence.

Additionally Arya, R. Parthiban, G. Gnanasambandan, Erode Mahesh, Pa. Vijay, Aari Arujunan, Venkat Renganathan, Kavitha Jawahar, Valaipechu Andhanan and KPY Bala were featured as themselves, praising the humanitarian act of Manickam.

[1][8] The film stars Samuthirakani portraying the titular character making his comeback as the lead actor after Lakshmy Ramakrishnan's Are You Ok Baby?

[11][12] The film is produced by GP Ravi Kumar, Chinta Gopala Krishna Reddy and Raja Senthil under GPRK Cinemas banner.

[3][13] The technical crew consists of M. Sukumar as the cinematographer and Vishal Chandrasekhar scoring the music and SP Raja Sethupathi[14] handling the editing.

[5] Principal photography took place across different locations in Kerala such as Kumily, Munnar, Meghamalai and Thekkady[4] and on 8 October 2023, it was announced that the filming has been wrapped.

[26] Abhinav Subramanian of The Times of India gave 2.5/5 stars and wrote "All in all, Thiru Manickam strives to evoke a strong emotional response, but leaves you feeling as unmoved as a block of granite.

"[27] Anusha Sundar of OTT Play gave 2/5 stars and wrote "A preachy, and too-good to be true story does not elevate this flatline family drama.

"[28] Jayabhuvaneshwari B of Cinema Express gave 2/5 stars and wrote "While Thiru.Manickam aspires to shine like the titular gem, the film ultimately feels more like polished glass—reflective on the surface, but lacking the brilliance within.