The song was also a number 1 single on the Hot Adult Contemporary Tracks charts.

A remixed version of "This One's for the Girls" was included on her 2008 compilation album Playlist: The Very Best of Martina McBride.

The song's lyrics are a salute to women of various ages (who are "about thirteen," "about twenty-five," and "about forty-two") dealing with the struggles of different phases of life–starting high school and facing new pressures, coping with uncertainty about a career, and reaching middle age–and tells them "You're beautiful the way you are."

McBride's first two daughters, Delaney and Emma, sing backing vocals on the song, as do fellow country singers Carolyn Dawn Johnson and Faith Hill.

Billboard Hot Country Singles & Tracks for the week of June 21, 2003.