[1] In 1751 he co-founded the Pennsylvania Hospital, the first medical facility in the American colonies, with Benjamin Franklin, and also volunteered his services there as both physician and teacher.

Having formed a favorable opinion of British hospitals in the course of his studies, Bond began trying to raise funds in 1750 to establish a place of care for both the sick and the mentally ill, particularly for the poor.

The hospital quickly drew attention as a center for medical advancement, especially in maternity care and the humane treatment of mental illness, a poorly understood area of medicine at the time.

[1] Thomas Bond also served as trustee of the University of Pennsylvania, where, in 1766, he began clinical lectures for the benefit of medical students.

When the American Revolutionary War broke out, the sixty-three-year-old doctor, along with his son, helped to organize the medical department of the Continental Army.

His epitaph reads: "In Memory of Thomas Bond, MD who practiced Physic and Surgery with signal reputation and success nearly half a century.