Thomas Cooper De Leon (May 21, 1839 – March 19, 1914) was an American journalist, author, and playwright.
Born in Columbia, South Carolina, his parents were Mordecai Hendricks de Leon and Rebecca Lopez.
His older brothers were the Confederate Surgeon-General David Camden de Leon and the writer and Confederate diplomat and propagandist Edwin de Leon.
Thomas Cooper de Leon served in the Confederate army from 1861 to 1865, and after the Civil War he edited The Mobile Register, The Gossip, and the Gulf Citizen (both Mobile papers; 1873–96).
He also wrote several plays, including the comedy-drama Pluck which was produced by Lawrence Barrett in 1873.